Use the Microsoft 365 admin center to enable or disable SMTP AUTH on specific mailboxes

  1. Open the Microsoft 365 admin center and go to Users > Active users.
  2. Select the user, and in the flyout that appears, click Mail.
  3. In the Email apps section, click Manage email apps.
  4. Verify the Authenticated SMTP setting: unchecked = disabled, checked = enabled.

    When you’re finished, click Save changes.